So good for the synthesis of fluorescent lipid probes

Posted on January 24, 2017 by Emilie Chabot

RAFT polymerization and the Bioruptor® enable the preparation of a new class of lipid-ended polymer conjugates presenting reactive sites regularly distributed along the polymer chain. This technic allows Salim Adjili and colleagues to create original fluorescent lipid-polymer probes for optical microscopy. Find out more

Using RIME for analysis of protein complex

Posted on January 24, 2017 by Emilie Chabot

The application of mass spectrometry for the analysis of protein complexes can be used in parallel with chromatin immunoprecipitation–sequencing experiments to provide information on both the cistrome and interactome for a given protein. Hisham Mohammed and colleagues developed the Rapid Immunoprecipitation Mass spectrometry of Endogenous protein (RIME) approach, a rapid and robust method to study chromatin and[…]