In this study,  researchers further investigated the molecular mechanisms behind resistance to radiotherapy. They further investigated  β1-integrin which was previously linked to cancer cell survival after irraditation. Among several findings, ectopic β1-integrin expression in S1 cells reduced RING1 levels and increased Rad51 accumulation. In contrast, β1-integrin depletion in T4-2 cells significantly increased RING1 protein levels[…]